National Institutes of Health
NIDA seeks to further advance its mission in the area of single cell biology. Since 2020, the NIDA-funded Single Cell Opioid Responses in the Context of HIV (SCORCH) consortium has generated single-nucleus datasets from human and animal postmortem brain tissue under conditions of HIV infection, antiretroviral therapy (ART), and/or substance exposure (e.g. opioids, cocaine, methamphetamine, and cannabinoids). Building on this Phase 1 foundation, NIDA will encourage research addressing critical questions on Substance Use Disorder (SUD) and interactions with HIV disease progression at the subcellular, cellular, or circuit levels in the Central Nervous System (CNS). Many new cutting-edge single cell approaches (e.g. interrogation of RNA splicing, non-coding RNAs, epigenomic or proteomic features, subcellular or synaptic localization and function, spatial interactions, cell-cell communication, or cellular connectivity) now enable novel hypothesis-generating studies. Along with data mining studies to identify candidate mechanisms or targets contributing to HIV/SUD interactions and hypothesis-driven studies to assess functional significance, we expect SCORCH Phase 2 to significantly advance our mechanistic understanding of SUDs and HIV in the CNS and identify targets for novel therapies. Grant authorities that allow NIDA to forecast this opportunity are 42 U.S.C. §§ 241 and 284
Up to $1,000,000
Total program funding: $5,000,000
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;
Who can apply: Government & Tribal, Small Businesses, Nonprofits, For-Profit Businesses, Schools & Colleges
Nationwide (USA)
Federal Government
This is a forecasted opportunity. Watch Grants.gov for the official notice; applications open once it is posted. You'll need SAM.gov (UEI) and Grants.gov registrations.
Substance Abuse and Mental Health Services Adminis
The purpose of this program is to support organizations in mobilizing and connecting community resources to increase access to long-term recovery support for people with substance use disorders and co-occurring substance use and mental disorders.
Last verified Oct 19, 2026
Centers for Disease Control and Prevention - ERA
The purpose of the R01 grant program is to (1) improve understanding of the risks and conditions associated with occupational diseases and injuries, (2) identify and evaluate methods to reduce risks and prevent or minimize exposure to hazardous workplace conditions, and (3) translate scientific findings into practical prevention strategies, interventions, and products that reduce work-related illnesses and injuries. The Research Project Grant (R01) supports a discrete, specified research project in scientific areas that reflect the investigator's expertise and interests and that align with the mission of NIOSH. Applicants must concisely describe the occupational health problem their proposal addresses and explain how the proposed research activities will lead to outputs that help address this problem. Applicants should clearly describe the expected impacts of the proposed research, both during the project period and beyond.
Last verified Oct 19, 2026
Centers for Disease Control and Prevention - ERA
This Notice of Funding Opportunity (NOFO) supports research to develop, implement, monitor, and evaluate technology-driven and cost-effective tools that reduce the global human rabies burden. It also measures progress toward canine rabies elimination, with an emphasis on high-burden countries. Priority research areas include: Electronic systems for tracking human and dog rabies vaccinations. Managing human rabies exposure investigations. Enhancing rabies laboratory information management systems. Modeling the economic impact of dog-mediated rabies interventions. Estimating rabies-susceptible dog populations. The research is intended to generate data-driven strategies that help accelerate progress toward global canine rabies elimination and protect public health.
Last verified Oct 19, 2026
Centers for Disease Control - NCCDPHP
This notice of funding opportunity (NOFO) will help build a workforce that's prepared to collect and use high-quality cancer data. This work is essential to understand the impact of cancer and inform public health action, research, and policy. This NOFO will support the National Program of Cancer Registries (NPCR) by: Strengthening the cancer surveillance workforce. Improving NPCR cancer data quality and completeness. Promoting the value and use of NPCR cancer surveillance data. The recipient will support certified Oncology Data Specialists (ODS) and other cancer surveillance professionals with education, credentialing, and professional development. These activities are intended to ensure the cancer surveillance workforce has the knowledge, skills, and resources to meet emerging needs and new technologies. The recipient will develop, maintain, and advance best practices, tools, and partnerships that support NPCR priorities and ensure timely, complete, and high-quality NPCR cancer surveillance data. This includes improving access to the expertise of ODS through technical assistance and guidance for NPCR registries and staff. In addition, the recipient will strengthen collaboration and communication strategies to promote the value and use of NPCR cancer surveillance data. The goal of these efforts is to help more people recognize that NPCR cancer surveillance data is a valuable resource for cancer research and public health decision-making. As a cooperative agreement, CDC will work closely with the recipient to provide technical assistance, support coordination with NPCR and partners, monitor progress, and help ensure a prepared cancer surveillance workforce that can meet current and future public health needs.
Last verified Oct 19, 2026