National Institutes of Health
The National Institute of Neurological Disorders and Stroke (NINDS) is interested in supporting the conduct of scientific research utilizing data from intermediate-size patient population expanded access protocols for ALS ("intermediate expanded access protocol for ALS", see Expanded Access Categories for Drugs (Including Biologics) ). Eligible intermediate expanded access protocols for ALS should: 1) provide access to an investigational drug or biological product for people with ALS, and 2) generate data to support research on the prevention, diagnosis, mitigation, treatment, or cure of ALS. The scientific research goal(s) informed by these data could include the investigational drug's or biological product's effect on biomarkers related to the pathophysiology of ALS or target engagement, the collection of safety or outcome information, such as survival or other significant medical events (e.g., hospitalization or need for ventilatory support), or patient experience data that are not specifically tied to assessing efficacy. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects.
Varies, see official page
Eligible applicants must be clinical trial sites that participate in a phase 2/3 or phase 3 efficacy clinical trial (designed to provide pivotal data to establish substantial evidence of effectiveness in support of a marketing application) supported by a U.S. based small business concern that is the FDA-designated sponsor of a drug or biological product which is the subject of an IND under section 505(i) of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 355(i)) to prevent, diagnose, mitigate, treat, or cure ALS. The definition of a small business concern can be found in section 3(a) of the Small Business Act (15 U.S.C. 632(a)).Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Who can apply: Government & Tribal, Nonprofits, Schools & Colleges, Small Businesses, For-Profit Businesses
Nationwide (USA)
Federal Government
This is a forecasted opportunity. Watch Grants.gov for the official notice; applications open once it is posted. You'll need SAM.gov (UEI) and Grants.gov registrations.
Substance Abuse and Mental Health Services Adminis
The purpose of this program is to support organizations in mobilizing and connecting community resources to increase access to long-term recovery support for people with substance use disorders and co-occurring substance use and mental disorders.
Last verified Oct 19, 2026
Centers for Disease Control and Prevention - ERA
The purpose of the R01 grant program is to (1) improve understanding of the risks and conditions associated with occupational diseases and injuries, (2) identify and evaluate methods to reduce risks and prevent or minimize exposure to hazardous workplace conditions, and (3) translate scientific findings into practical prevention strategies, interventions, and products that reduce work-related illnesses and injuries. The Research Project Grant (R01) supports a discrete, specified research project in scientific areas that reflect the investigator's expertise and interests and that align with the mission of NIOSH. Applicants must concisely describe the occupational health problem their proposal addresses and explain how the proposed research activities will lead to outputs that help address this problem. Applicants should clearly describe the expected impacts of the proposed research, both during the project period and beyond.
Last verified Oct 19, 2026
Centers for Disease Control and Prevention - ERA
This Notice of Funding Opportunity (NOFO) supports research to develop, implement, monitor, and evaluate technology-driven and cost-effective tools that reduce the global human rabies burden. It also measures progress toward canine rabies elimination, with an emphasis on high-burden countries. Priority research areas include: Electronic systems for tracking human and dog rabies vaccinations. Managing human rabies exposure investigations. Enhancing rabies laboratory information management systems. Modeling the economic impact of dog-mediated rabies interventions. Estimating rabies-susceptible dog populations. The research is intended to generate data-driven strategies that help accelerate progress toward global canine rabies elimination and protect public health.
Last verified Oct 19, 2026
Centers for Disease Control - NCCDPHP
This notice of funding opportunity (NOFO) will help build a workforce that's prepared to collect and use high-quality cancer data. This work is essential to understand the impact of cancer and inform public health action, research, and policy. This NOFO will support the National Program of Cancer Registries (NPCR) by: Strengthening the cancer surveillance workforce. Improving NPCR cancer data quality and completeness. Promoting the value and use of NPCR cancer surveillance data. The recipient will support certified Oncology Data Specialists (ODS) and other cancer surveillance professionals with education, credentialing, and professional development. These activities are intended to ensure the cancer surveillance workforce has the knowledge, skills, and resources to meet emerging needs and new technologies. The recipient will develop, maintain, and advance best practices, tools, and partnerships that support NPCR priorities and ensure timely, complete, and high-quality NPCR cancer surveillance data. This includes improving access to the expertise of ODS through technical assistance and guidance for NPCR registries and staff. In addition, the recipient will strengthen collaboration and communication strategies to promote the value and use of NPCR cancer surveillance data. The goal of these efforts is to help more people recognize that NPCR cancer surveillance data is a valuable resource for cancer research and public health decision-making. As a cooperative agreement, CDC will work closely with the recipient to provide technical assistance, support coordination with NPCR and partners, monitor progress, and help ensure a prepared cancer surveillance workforce that can meet current and future public health needs.
Last verified Oct 19, 2026